BioWhite - Scale-up of cellulose micro particles

Titania nanoparticles are currently used as a base for most white pigments. However, those particles are facing regulations in health-sensitive industries and are lacking biocompatible alternatives. Yang et al. have developed a patented, cellulose white pigment for use in cosmetics, food and pharma formulations.[1] Although the synthesis of this cellulose white pigment at laboratory scale is straightforward, its scale-up is challenging low volume yield, poor yield, high total product cost, long cycle time and low throughput. Currently, the scale-up was successful until the 100 L scale. This project was financed by Innosuisse and was done in collaboration with Lukas Schertel and his team (now Seprify).

[1] H. Yang, G. Jacucci, L. Schertel, S. Vignolini, ACS Nano 2022, 16, 7373